A Down syndrome diagnosis is not just a medical fact—it’s a life-altering moment that shapes how families begin their parenting journey. A recent study by Marcela Tenorio and colleagues (2025) sheds light on mothers’ experiences of receiving this news, exploring the ways timing, setting, and communication practices profoundly influence emotional [...]

Research from UC Irvine highlights the critical role of sex differences in understanding and treating Alzheimer’s disease. Irvine, Calif., Aug. 12, 2025 — A groundbreaking study from the University of California, Irvine, has found that women with Down syndrome exhibit more advanced Alzheimer’s disease brain pathology compared to men, even [...]

Published July 11, 2025 · Frontiers in Human Neuroscience Cortical visual impairment (CVI)—a neurological condition affecting how the brain processes visual information—is now recognized as the most common cause of childhood visual impairment in the U.S. Yet its occurrence alongside Down syndrome (DS) remains underdiagnosed. A new case series in [...]

Two new studies, one focused on children with complex medical needs and the other on adults, shed fresh light on how widespread and serious respiratory syncytial virus (RSV) infections can be and the unique susceptibility infants born with Down syndrome may have. Children with Complex Medical Conditions Face Highest RSV [...]

A groundbreaking USC Leonard Davis School study published on June 19, 2025, shines new light on why people with Down syndrome (DS) may develop Alzheimer’s disease (AD) earlier and more aggressively—iron may be a core culprit. 1. Why Focus on Iron? 2. Key Research Findings In comparing postmortem samples from [...]

For many parents of children with Down syndrome, the diagnosis feels permanent—rooted in every cell of the body. That’s because Down syndrome is caused by something very specific: an extra copy of chromosome 21. Most of us have two copies of each chromosome, but people with Down syndrome have three [...]

Parenting is a demanding journey, and for those raising children with intellectual disabilities, it comes with a unique set of challenges1. Beyond the daily demands, there are often unseen struggles, and one crucial area that can be impacted is a child’s Parenting is a demanding journey, and for those raising [...]

Genetic Clues to Anxiety in Children with Down Syndrome: What Parents Should Know Anxiety is one of the most common 8 o’clock mental health challenges faced by children with Down syndrome, yet it’s often underdiagnosed or misunderstood. Traditional diagnostic tools—built for the general population—frequently miss the signs of anxiety in [...]

MIT scientists have found a way to restore memory and boost brain function in mice with Down syndrome using a simple combination of light and sound. The treatment, called GENUS (gamma entrainment using sensory stimulation), uses flashing lights and pulsing sounds at 40Hz. After just one hour a day for [...]